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|''||''| '||''|. | '||' '|' '|| ||' | || || || ||| || | ||| ||| ||| || ||''|' | || || | |'|..'|| | || || || |. .''''|. || | | '|' || .''''|. .||. .||. '|' .|. .||. '|..' .|. | .||. .|. .||. ..|'''.| '||''''| '|. '|' |''||''| '||''''| '||''|. .|' ' || . |'| | || || . || || || ||''| | '|. | || ||''| ||''|' '|. . || | ||| || || || |. ''|....' .||.....| .|. '| .||. .||.....| .||. '|' SECOND OPINION FAQ / Walkthrough v1.1 Final, December 10, 2006 by Aaron "rmz" Ramsey <rmz (at) bemaniso (dot) ws> TABLE OF CONTENTS VERSION HISTORY INTRODUCTION Introduction to Trauma Center [0.01] What's New to Second Opinion? [0.02] Controls [0.03] Tools/Items [0.04] Gameplay Overview [0.05] WALKTHROUGH Episode 1-1: Standard Procedure [1.01] Episode 1-2: Learning the Ropes [1.02] Episode 1-3: A Farewell [1.03] Episode 1-5: Singing the Blues [1.05] Episode 1-6: A Real Doctor [1.06] Episode 1-8: Life or Death [1.08] Episode Z-1: From Overseas [Z.01] Episode 2-1: Dormant Ability [2.01] Episode 2-3: Striving for Asclepius [2.03] Episode 2-4: Awakening [2.04] Episode 2-6: Just Let Me Die [2.06] Episode 2-9: Please Let Me Live [2.09] Episode 2-11: For the Greater Good [2.11] Episode Z-2: Miracle [Z.02] Episode 3-2: GUILT [3.02] Episode 3-4: Something Precious [3.04] Episode 3-6: An Explosive Patient [3.06] Episode 3-8: Caduceus on a Plane [3.08] Episode 3-10: Pandora's Box [3.10] Episode Z-3: Pursuit [Z.03] Episode 4-2: Race for the Cure [4.02] Episode 4-4: Stepping Up [4.04] Episode 4-6: The First Step [4.06] Episode 4-7: Medical Research [4.07] Episode 4-8: The Next Step [4.08] Episode 4-9: Progress [4.09] Episode 4-10: Prolonged Struggle [4.10] Episode Z-4: Transplant [Z.04] Episode 5-2: Under the Knife [5.02] Episode 5-3: Shifting GUILT [5.03] Episode 5-4: GUILT Evolves [5.04] Episode 5-6: Infection [5.06] Episode 5-8: A Devil [5.08] Episode 5-9: Death Awaits All [5.09] Episode Z-5: Sayonara [Z.05] Episode 6-3: Relapse [6.03] Episode 6-4: Second Opinion [6.04] Episode 6-6: The Future of GUILT [6.06] Episode 6-7: Fallen Heroes [6.07] Episode 6-8: Vulnerability [6.08] Episode X-1: Kyriaki [X.01] Episode X-2: Deftera [X.02] Episode X-3: Triti [X.03] Episode X-4: Tetarti [X.04] Episode X-5: Pempti [X.05] Episode X-6: Paraskevi [X.06] Episode X-7: Savato [X.07] Ending [E.ND] GUILT STRATEGIES Kyriaki [G.01] Deftera [G.02] Triti [G.03] Tetarti [G.04] Pempti [G.05] Paraskevi [G.06] Savato [G.07] CREDITS/LEGAL -------------------------------------------------------------------------------- Version History -------------------------------------------------------------------------------- v0.1, 11/22/06 - FAQ started, filling in walkthroughs for up to Episode 6-6 since that's the farthest I've gotten so far. The remaining stages will be added once I get to them... X_x v0.2, 11/24/06 - Initial FAQ completed, still not complete but it's full enough for an initial release. I still need to add details for the later missions, but most of the content is there at this point. v0.3, 11/25/06 - Added Triti tips from Ryn. v0.5, 11/30/06 - Added 6.7 and 6.8 user-submitted tips (since I've been too busy as of late to play at all, much less actually progress any farther). Added space for X Mission strategies for future expansion (even though I know nobody who has even cleared the first one yet). Also fixed a few typos. v0.51, 12/01/06 - Added Paraskevi tips from Ryn. v1.0, 12/03/06 - Added my own info for the last two missions. Added X Mission info, strategies, and script elements. Thanks a million to Micah<Malkis> for all of his extremely detailed X Mission information! v1.1, 12/10/06 - X Mission strategies updated, added information about tool degredation. Final version of this FAQ, more than likely. ================================================================================ + + + + + I N T R O D U C T I O N + + + + + ================================================================================ -------------------------------------------------------------------------------- Introduction to Trauma Center [0.01] -------------------------------------------------------------------------------- What is Trauma Center? I'm glad you asked. Trauma Center is a cult hit videogame (now a videogame series, I suppose) designed by Atlus. The first game, "Trauma Center: Under the Knife" (entitled "Caduceus: Surgical Operation" in Japan) was released for the Nintendo DS in 2005 and quickly became a sleeper hit and instant cult classic among players all over the world. Now, Under the Knife has been updated and remade for the new Nintendo Wii, in the form of "Trauma Center: Second Opinion" (or "Caduceus Z" in Japan). The remake sports upgraded, stylized graphics, redone character portraits, new tools, a whole new final chapter, and a handful of new missions interspersed that put you in the shoes of a new surgeon, Dr. Nozomi Weaver, many of which make use of the Wii remote's unique functionality. The mission "An Explosive Patient" has also been completely reworked to incorporate some of the Wii remote's unique features. In typical Atlus fashion, both the original game and Second Opinion have seen supply issues arise, as demand for the games exceeds the number of copies Atlus has produced. Under the Knife saw a reprint in 2006 due to demand, and Second Opinion already seems fairly difficult to find right out of the gate. -------------------------------------------------------------------------------- What's New to Second Opinion? [0.02] -------------------------------------------------------------------------------- I glossed over this in the previous section, but now let's go into specifics: * A new playable character, Dr. Nozomi Weaver. She also has the Healing Touch. * A completely new Chapter 6, containing a so-called "eighth GUILT." * New tools and items: > Defibrillator > Penlight > Camera flash * Reworked functionality for some existing tools: > Membranes no longer need to be massaged (as there is no Hand tool). > Drain only needs to be held in place to be used. > Syringe does not need to be "drawn up," only held in place. > The defibrillator is now used in place of "heart massages." > There is no Healing Touch tool to select -- simply hold Z and B and draw the star at any time. * Reworked missions: > An Explosive Patient is completely redone. > All of Chapter 6 is completely replaced. > A few missions have had their titles retranslated or changed. * New, even harder X missions. How they made them harder than the DS version's is beyond me. * Three difficulty settings, selectable for each operation (Easy, Normal, Hard). The X Missions have their own difficulty level entitled "Extreme." * Able to replay any mission at any time, on any difficulty of your choosing. -------------------------------------------------------------------------------- Controls [0.03] -------------------------------------------------------------------------------- Trauma Center: Second Opinion makes use of the so-called "Nunchuk Style," which means that you hold the Wii remote in one hand (usually the right) and the Nunchuk in your other (usually the left). To switch to a tool, you simply point the Nunchuk's analog stick in one of the eight directions. How cool is that? No more hunting and pecking on the touch screen. Antibiotic Gel * Forceps | Syringe * | * | / | / |/ Scalpel *-------O-------* Suture /| / | / | * | * Ultrasound | Drain / Magnifier * Laser This makes some of the later missions far easier, in my opinion. Thanks to this control setup, you can switch between Ultrasound -> Scalpel -> Laser -> Gel faster than you can say "dead Kyriaki." For using the actual tools, you use the Wii remote on the screen like a laser pointer. In fact, the in-game pointer reticule seems to be designed to look like a laser pointer. Anyway, you move the pointer over whatever you want to use your tool on and you just press the appropriate button. For control specifics for each tool, read the next section, "Tools/Items." Finally, you can press the - (Minus) key on your Wii remote to auto-skip text in cutscenes or in an operation. Helpful when you keep having to retry an operation preceded by a lengthy cutscene! You'll know this is activated because the word "Skip" will appear in the lower-right corner of the screen. Press - again to return dialogue to normal mode. -------------------------------------------------------------------------------- Tools/Items [0.04] -------------------------------------------------------------------------------- Let's go over the tools and items in the game, along with what they're used for and how you operate them. * Antibiotic Gel * > Use: instantly heal small cuts, sterilize synthetic membranes, sterilize sutures, raise vitals slightly, repel some strains of GUILT > Control: point at the area you want to gel and press either A or B. * Forceps * > Use: extract items buried in tissue, pick up other small items, transport objects to/from trays, pinch large lacerations closed > Control: point at the object that you want to grab with the forceps, then press both A and B at the same time (like you're squeezing on a pair of forceps, right?). To pull a laceration closed, use the forceps on one side of the laceration and drag the pointer over to the other side. * Scalpel * > Use: make incisions, excise tumors and other objects, damage some strains of GUILT > Control: point at the object that you want to cut and press either A or B. To cut along a line, just hold down the button and move your pointer along the line. * Ultrasound * > Use: detect objects hidden below the surface of an organ > Control: point at the area that you want to scan and press either A or B. * Magnifier * > Use: zoom in on an area to get a closer look > Control: point at the area that you want to zoom in on and press either A or B. * Laser * > Use: burn away polyps, stun/damage some strains of GUILT > Control: point at the area that you want to pew-pew and press either A or B. * Drain * > Use: drain various fluids from various objects > Control: point at the fluid that you want to drain and hold either A or B until "OK" appears. * Suture * > Use: stitch large lacerations or incisions closed > Control: hold either A or B, then draw a zig-zag pattern across the part that you want to suture. If your zig-zag isn't good enough, you'll have to do it again. * Syringe * > Use: inject stabilizer into patient to raise vitals, inject anti- inflammatory into aneurysms, inject serums to weaken/destroy some strains of GUILT > Control: first, point at the vial that you want to grab fluid out of, then hold A or B to fill up the syringe. Then, point to the area that you want to inject into and hold A or B once more, keeping the syringe steady as it empties. * Defibrillator * > Use: brought up automatically on the screen when your patient suffers cardiac arrest -- use it to restart their heart! > Control: first, push both the Wii remote and the Nunchuk towards the screen to press the defibrillator pads onto the patient's chest. Then, press Z and B simultaneously when the voltage meter is in the small "window" on the right-hand side of the gauge. It may take a few tries, and timing is everything! * Healing Touch * > Use: use superhuman concentration and focus to slow down time temporarily. You can normally only use the Healing Touch once per operation. > Control: hold down Z and B, then draw a star shape on the screen in the following pattern: 2 4 5 1 3 6 * Bandages * > Use: bandage a sutured incision; used at the end of every operation > Control: when your have sutured your original incision, gel the incision and then pick up the roll of bandages from the tray with A or B. Point at one end of the incision, hold A or B, and then point at the other end to stretch the bandage across. Release A or B with the bandage laid over the sutures and the bandage will be placed. * Synthetic Membrane * > Use: seal a hole left behind by an excised tumor > Control: after the tumor is excised, place the membrane on the hole with your forceps and then apply gel on top of the membrane. You don't have to massage the membrane in separately like in Under the Knife -- that's now part of the gelling process. * Penlight * > Use: provide light during low-light conditions > Control: select the penlight on the side of the screen with A or B (just as you would a roll of bandages) and position the pointer. Press A or B to lock the light in place. * Camera Flash * > Use: provide (temporary) light during low-light conditions > Control: press A or B on the camera icon to make the camera flash. Quick, fix up the patient before the light fades away! -------------------------------------------------------------------------------- Gameplay Overview [0.05] -------------------------------------------------------------------------------- The basic flow of gameplay in Trauma Center divides the action into two phases: cutscenes and operations. You will generally get a cutscene between each operation, but at other times you may get multiple cutscenes (or operations) in a row. The cutscenes advance the story and help explain what your next operation is all about, or what the results of your previous operation were. They also help to explain the game's story, such as what the heck this wacky GUILT thing is anyway. When an operation starts, you'll get a quick briefing on the patient's condition and what your objectives are for the operation. These objectives will often be painfully obvious (i.e., destroy the GUILT) but other times they can help to summarize a potentially confusing string of dialogue into something meaningful. During an operation, you have to accomplish all of your objectives, and finish the operation (this usually includes suturing your original incision, gelling it, and placing a bandage) before the timer expires. You'll have to balance your use of tools, though -- as you use a tool, its icon color will turn yellow, then red, and it will eventually break for a short while, at which point it will become unusable until its icon returns to normal. After the operation, you'll receive a score and rank based on your performance. The highest rank is S: Master Surgeon. On Hard difficulty there is an even higher XS rank that can be obtained. ================================================================================ + + + + + W A L K T H R O U G H + + + + + =====================The patient's life is in your hands!======================= -------------------------------------------------------------------------------- Episode 1-1: Standard Procedure [1.01] Overview: Lacerations and foreign objects in upper right brachium. Requires removal of the foreign objects and suturing of any wounds. Objectives: * Suture any lacerations. * Extract fragments of glass from underneath the patient's skin. GUILT Faced: (none) -------------------------------------------------------------------------------- Welcome, Dr. Stiles. The first procedure isn't anything special, but if you're new to Trauma Center then it could pose a mild challenge, so try your best. Even if you were a pro with the DS version, this is a good mission to get comfortable with the Wii controls on. You'll see some glass stuck in the patient, as well as some lacerations. Select the forceps and pull the glass out -- pull it out the same direction it went in, and pull it ALL THE WAY OUT, until the tip clears the wound, otherwise you'll hurt the patient and the glass will stick back in. Once you've managed that, drop the glass in the extraction tray to your right. For the lacerations, use your suture tool to stitch the wounds closed. Then you'll have to make an incision in the patient's arm and pull some more glass out, just like before. When you're done, suture up your incision, apply some gel until you see "OK," and then roll a bandage on. Get used to this -- you'll need to do the same three-step procedure in just about every operation in the game. In general, just listen to what Mary tells you and do what she says. No sweat. -------------------------------------------------------------------------------- Episode 1-2: Learning the Ropes [1.02] Overview: Tumor confirmed at the surface of the stomach. It should be removed before it becomes malignant. Objectives: * Excise and remove the tumor in the patient's distal stomach. GUILT Faced: (none) -------------------------------------------------------------------------------- In this operation, you'll learn a procedure that you'll use a few more times, so try to memorize it. Dr. Kasal calls it the "Powell method," and it is as follows: 1. Use the ultrasound to find a tumor under the surface of the organ. 2. Once a tumor is visible, use your scalpel to cut down the center of it. 3. Use the drain to drain the fluid from inside the tumor. 4. Use your scalpel around the outside of the tumor, tracing the yellow dots. 5. Extract the tumor with your forceps and drop it in the tray. 6. Take a synthetic membrane from the tray to your left and put it on the hole. 7. Rub some gel on the membrane until "OK" appears. And that's it. Mary will help you if you have trouble remembering. There's not much here that should give you any trouble. Good luck! -------------------------------------------------------------------------------- Episode 1-3: A Farewell [1.03] Overview: Multiple tumors confirmed in the pancreas. They may lead to a loss of stamina, so immediate removal is highly recommended. Objectives: * Excise and remove all tumors from the patient's pancreas. GUILT Faced: (none) -------------------------------------------------------------------------------- Same as before, only there are multiple tumors to extract. Put your knowledge of the Powell method to use here! Again, Mary is here to give you a helpful reminder if you need it. -------------------------------------------------------------------------------- Episode 1-5: Singing the Blues [1.05] Overview: Polyp clusters confirmed in the trachea. Due to internal hemorrhaging, a hemostatic laser procedure is necessary. Objectives: * Drain the overflowing blood. * Locate the source of the patient's distress. * Use the laser to remove it. GUILT Faced: (none) -------------------------------------------------------------------------------- This is probably the first mission that you might have a risk of losing your patient on. However, the only way that would really happen on this operation would be if you let the burn marks bleed into infinity and never gel them. In any case, zoom in on the first cluster and switch to your drain. Suck up the blood, then laser off the polyps. Once you've burned off a few, switch over to the gel and smear some across the burn marks. You can wait until you've gotten all of the polyps to put on any gel, but bleeding could start and it's a little safer to gel more frequently. If you're going for the quickest possible clear, though, feel free to burn everything off at once. Afterwards, zoom out and there will be another cluster. Deal with that one in the exact same way. After that, there will be a couple more. More of the same -- if the patient's vitals get too low, inject some stabilizer (the green vial) to raise his vitals. And that's that! -------------------------------------------------------------------------------- Episode 1-6: A Real Doctor [1.06] Overview: Multiple tumors confirmed in the small intestine, resulting in several other inflammations. Immediate removal is required. Objectives: * Treat the inflamed epithelium in his small intestine. * Excise and remove all tumors in the area. GUILT Faced: (none) -------------------------------------------------------------------------------- This is just like "A Farewell," except that before you start excising the tumors, you will have to inject some anti-inflammatory into the little purple dots all over the place. Once those are all gone, ultrasound and remove the tumors just like you've done so many times before. Use the stabilizer if you need it, but you really shouldn't have any trouble with vitals for this one. After you're finished with the tumors, Angie will ask you to use the ultrasound to ping around looking for anything unusual, but you won't see anything, so just suture, gel, bandage, and you're done. -------------------------------------------------------------------------------- Episode 1-8: Life or Death [1.08] Overview: Patient suffered cardiac arrest as a result of a car accident. Multiple lacerations of the epithelium in the abdomen. Objectives: ...F-First we need a pulse...We have to get a pulse. GUILT Faced: (none) -------------------------------------------------------------------------------- Oh boy, a new tool! This mission lets you play with the defibrillator to jump- start the patient's heart. "Push" the remote and Nunchuk towards the screen to press the defibrillator pads onto the patient, then press Z and B at the proper time. It may take a few tries, but that's okay. Once his heart is restarted, get to work on the glass shards. Just like before -- pull them out in the same direction as they went in. If his heart stops again, use the defibrillator the same as you did the first time. After you finish with the glass, a large gash will open and a *HUGE* piece of glass will pop out of it. Pull it out -carefully- and then place it in the tray. Things will go downhill (again) and you'll see a star being drawn on the screen, while time seems to slow down temporarily. Hurry and suture that wound! This will be explained soon, don't worry. -------------------------------------------------------------------------------- Episode Z-1: From Overseas [Z.01] Overview: Comminuted fracture in patient's radius bone. There also seems to be internal hemorrhaging. Treat bleeding, then rebuild the broken bone. Objectives: * Collect fragments of his radius and ulna. * Set the radius properly for healing. * Return the fragments to their original location and rebuild the patient's radius and ulna. GUILT Faced: (none) -------------------------------------------------------------------------------- This is a fun mission designed specifically for Second Opinion that uses the Wii remote. First, collect all of the bone fragments using your forceps. Once you have them all, pull the radius (the uppermost bone, the one that's sticking out kind of diagonally) downwards into alignment with the other bones. Once that's done, you can start reconstructing the bone. Pick up a bone fragment, and find where it fits by rotating it around with the Wii remote (twist your wrist like you're opening a door). Once you find where it lines up, let go of the fragment and it should drop into place. If it doesn't work, try it again. If it still doesn't go, it's possible that the piece doesn't quite fit into that spot, or you're not lining it up quite right. Once you have all of the pieces set, you'll notice that you're still missing one. Use the ultrasound to find it, then put it in place. Rub some gel on the bones to bond them (I wish it were this easy in real life!) and then you're basically done. Congratulations! -------------------------------------------------------------------------------- Episode 2-1: Dormant Ability [2.01] Overview: Multiple thrombi present due to waste blockage. Immediate removal is required to prevent further complications. Objectives: * Remove all thrombi in the vessels. GUILT Faced: (none) -------------------------------------------------------------------------------- This is a mission that will get you practicing your rapid-fire tool switching. To take out a single thrombus, you'll need to do the following: * Pinch the thrombus in place with your forceps. * Cut open the tissue with your scalpel. * Drain the cut with the drain (this will suck up the thrombus with it). * Gel the cut. At a certain point, things will start to go crazy as they're apt to do in the Trauma Center universe. You'll see time slow down again, and use that chance to snatch up all of the thrombi that you can possibly manage. Start from the upper-right and work your way backwards -- it's always smarter to go after the ones that are just about to reach the spleen, since those will cause your vitals to drop. You shouldn't have too much trouble, but if you do, inject some stabilizer and keep moving. Speed is essential here! -------------------------------------------------------------------------------- Episode 2-3: Striving for Asclepius [2.03] Overview: Personal training exercise. Gain focus and practice superhuman concentration for self-betterment. Objectives: * Master the Healing Touch. GUILT Faced: (none) -------------------------------------------------------------------------------- Now you finally get to control the Healing Touch. Once per operation, you will be able to use this technique to slow down time temporarily to buy you precious time to perform multiple tasks or raise vitals just as things start to get out of hand. To complete this mission, you must successfully pull off the Healing Touch move several times. To perform it, hold down Z and B and then draw a star on the screen, in the following pattern: 2 4 5 1 3 6 That is, start in the lower-left, draw to the top, then lower-right, then upper- left, then upper-right, then back to the lower-left where you started. If it looks enough like a star (and you only used five lines), the Healing Touch will activate. Well, not in this mission, but this is just for practice. If you're having trouble drawing the star, make sure that you don't draw any "extra" lines. I oftentimes see that I draw a small line in the lower-right before I actually begin drawing the star, and the game seems to only recognize the first five lines you draw, making it impossible for me to complete the star. Work on it, practice, and keep your wrist steady! Practice makes perfect, and you've got to know it well enough to do it under stress (which is almost always when you'll be using it). -------------------------------------------------------------------------------- Episode 2-4: Awakening [2.04] Overview: Multiple aneurysms have formed on the surface of the large intestine. Requires sedative treatment and suturing of affected vessels. Objectives: * Treat the aneurysms on the outer membrane of the patient's large intestine. GUILT Faced: (none) -------------------------------------------------------------------------------- This one was a pain on the DS, but it's a bit more manageable here. You need to zoom in on the aneurysm, inject the brown serum (anti-inflammatory) to shrink them down, and then cut them out with your scalpel. Once they're cut, you can extract them. After that, drain the cut, pull one end of the vessel over to the other with your forceps, and then suture the point where they connect. It seems like a lot, but once again being able to switch tools with your free hand certainly helps make this a lot easier to manage. If you see any aneurysms growing large while you're working, drop everything and inject some anti-inflammatory into them to keep them from bursting. A single bursting aneurysm will lower your vitals by a decent chunk -- and multiple bursts at once will almost certainly kill your patient, or at least put them on the edge of death. To make things a little more manageable, try shrinking all of the aneurysms on your screen at once, then cutting them all, then extracting them all. That way, you won't have to worry about any of them bursting while you're working on one! In any case, working quickly is the key here. But then again, that should go without saying by this point. -------------------------------------------------------------------------------- Episode 2-6: Just Let Me Die [2.06] Overview: Several bleeding lacerations found in the right lung. Patient's vitals are unstable, necessitating extreme caution. Objectives: * Treat all injuries within the thoracic cavity. GUILT Faced: (none) -------------------------------------------------------------------------------- This one is pretty straightforward -- or dare I say it -- easy. Just deal with the lacerations. Pinch and suture the gaping one, and just suture the regular ones. Gel any little ones. Not much to worry about here, really. What's that? You want more excitement? Okay, you've got it. See you in the next operation. -------------------------------------------------------------------------------- Episode 2-9: Please Let Me Live [2.09] Overview: Hemorrhaging lacerations have re-formed in the right lung. Please conduct an investigation while performing hemostatic treatment. Objectives: * Treat any bleeding injuries within the thoracic cavity. * Discover the source of the lacerations. GUILT Faced: Kyriaki -------------------------------------------------------------------------------- It's the same girl as last time, but her wounds are back. What's going on? Open her up and treat the wounds just like before. However, this time I would highly advise leaving one wound open, pumping her vitals to maximum, and then closing the last wound. Why? From this point on in the game, almost every operation will have multiple "phases," and the game will move on to the next phase once you heal all of a set of wounds. So, if you leave one open and then raise your vitals to maximum, you ensure that you'll begin the next phase with as high of vitals as possible. This quickly becomes *essential* to survival. So, pump her vitals and then suture the last wound. Suddenly, another wound forms. What the...?! Use your ultrasound and you'll see a little blue thing swimming around inside her lung. Get a good look. This is the first strain of GUILT, the terrorist-manufactured virus that you'll be dealing with primarily for the rest of the game. This particular one is called Kyriaki, and it attacks by swimming around and creating lacerations in its wake. Let's get down to business. First, locate the Kyriaki with your ultrasound, then switch to the scalpel and cut directly on top of it. If your aim is true, the Kyriaki will be exposed and begin swimming around on top of the organ, at which point you can shoot it with the laser. Keep lasering it until it stops moving and "Defeat" appears on the screen. Congratulations, you've killed it! Oh wait, there's more. Kill any more Kyriaki that appear, and then once you've finished up with those you'll see three big lacerations appear in the shape of an asterisk. Ping around with the ultrasound and you'll see one big freaking Kyriaki. This is a mature specimen. Treat it the same way, only that after you laser it, it will burrow back under the surface and you'll have to cut it out again. Do this a few times and it, too, will die. Congratulations! As a general rule of thumb, unless the patient's vitals get *really* out of hand, I would recommend ignoring the lacerations that the Kyriaki make, and just focusing on destroying the little buggers. Once they're dead, you'll have plenty of time to suture all of the wounds. This won't always be the case in later missions where you have lots of stuff going on and the patient's vitals just can't take it, but if it's just Kyriaki all by itself then you may be safe just leaving the lacerations alone until they're all dead. -------------------------------------------------------------------------------- Episode 2-11: For the Greater Good [2.11] Overview: Mitral prolapse and regurgitation. Since complications may arise, it is necessary to replace the valve with a synthetic one. Objectives: * Replace a valve in her heart with a synthetic one. GUILT Faced: (none) -------------------------------------------------------------------------------- Not a whole lot to say here -- follow Angie's directions and use the defibrillator when necessary. It can be a little tricky figuring out how you're supposed to suture in the new valve -- best I can tell, just suture directly across the middle of the thing. Anyhow, there's no real strategy here except raising vitals when needed, jump-starting the patient's heart when needed, and doing what Angie says. You can do it. -------------------------------------------------------------------------------- Episode Z-2: Miracle [Z.02] Overview: Extraction of an unusual tumor present in the large intestine. Patient's vitals may fluctuate abnormally. Objectives: * Extract any tumors in the patient's large intestine. GUILT Faced: (none) -------------------------------------------------------------------------------- You'll face a new sort of tumor here, one that can regenerate itself and others. As far as I can tell, the best (only?) way to deal with these things is to take them all out at once, otherwise they'll regenerate each other. Use your scalpel on the three little "legs" of each tumor, then once those are all gone, extract each one. You shouldn't have too much trouble, but you'll have to be on your toes because these guys can regenerate pretty quickly if you move too slow. -------------------------------------------------------------------------------- Episode 3-2: GUILT [3.02] Overview: Positive Chiral reaction -- Kyriaki bodies detected. Immediate removal is required to prevent further complications. Objectives: * Remove the Kyriaki. GUILT Faced: Kyriaki -------------------------------------------------------------------------------- This mission is just a test, and is more or less identical to "Please Let Me Live." Suture the wounds (all but one anyhow), raise vitals to max, and then suture the last wound. Kill the Kyriaki via the ultrasound -> scalpel -> laser method. Rinse and repeat for the mature one. You should have no trouble with this if you beat Please Let Me Live. Use your Healing Touch if you have to but you shouldn't need it -- just keep an eye on those vitals and try to kill the Kyriaki before they make too many lacerations! -------------------------------------------------------------------------------- Episode 3-4: Something Precious [3.04] Overview: Chiral reaction positive -- Deftera bodies detected. Complete removal from the stomach and lungs is required. Objectives: * Remove the GUILT from...the patient's stomach and lungs. GUILT Faced: Deftera -------------------------------------------------------------------------------- Oh boy, a new strain of GUILT. These guys look exactly like fantail goldfish, don't ask me why. Maybe someone at Atlus keeps an aquarium? Anyway, as Tyler will tell you, Deftera come in two flavors -- red and blue. If two opposite-color Deftera come into contact with one another, they will begin trying to eat each other, but since they're of equal strength they'll just kind of sit there. When they join together like this, pull out the drain and start sucking away at them. When you see "OK," they'll split up and swim around some more. When they combine again, repeat the process. Eventually they'll die, then the trickier part comes along. After you kill the first two, you'll move to another part of the patient's body where you'll see *two* pairs of Deftera, two red and two blue. The challenge comes in that if a pair of Deftera are combined, they will break apart and Bad Things will happen if another Deftera collides with them. Additionally, you'll also get a vitals drop if two like-colored Deftera collide. So, once an opposite-colored pair of Deftera start eating away at each other, smear some gel around them. This will function as a sort of shield to ward off the other Deftera temporarily while you concentrate on draining the two that are combined. If you have trouble with polyps forming (due to collisions), burn them off and gel the burn marks if necessary, but you might want to save that until the end. It's up to you and it depends on the situation, really. As always, don't be afraid to pump the patient's vitals up a bit if things get hairy. Anyhow, once the Deftera are dead, extract them and place them on the tray. Nice work! -------------------------------------------------------------------------------- Episode 3-6: An Explosive Patient [3.06] Overview: It's a bomb. Blindly cutting at it would be extremely...bad. Cross your fingers and listen to Dr. Myers. Objectives: * Dismantle the bomb. GUILT Faced: (none) -------------------------------------------------------------------------------- This mission is completely redone for Second Opinion, so unfortunately Under the Knife FAQs won't help you here :P First, you'll see four screws. Use your scalpel and twist the Wii remote around like a screwdriver to remove the screws. Beware, they don't all turn in the same direction, and if you mess up three times, the bomb will detonate! Luckily, if you look closely on the panel you'll see some markings that tell you which direction the screws turn. If you make enough mistakes, Cybil will point this out to you, so you can't really miss it. Now, then, once the front panel is off you'll zoom in on the voltage regulator. You'll have to use your forceps to pull out the plugs and reposition them so that the voltage level matches up with the pink line on the gauge. For me, it was the first slot on the left side and the second slot from the bottom on the right side, but I'm not sure if it's the same every time. Anyhow, once you find the right combination you'll move on to the core. Use your laser to shoot off the spinning panels on the core. Be careful not to shoot a flashing panel, or the bomb will go off! The flashing panels move around on a set interval, so it's wise to stop lasering when the panels are just about to move, then resume after you see where they went to. Also, I wouldn't recommend trying to laser panels that are on the top, bottom, or sides of the sphere (that is, ones that aren't directly facing you) because the game may think that you're trying to shoot at a panel that is in front of it, which can detonate the bomb if the panel isn't there. Play it safe and only shoot for panels when they're in plain sight. Finally, the core will be exposed and you'll have to shoot it. However, there will be red spinning things flying around the core, and if you so much as *touch* one of these with your laser, the bomb goes off. So, be -really- careful and be light with your trigger finger. If there's any danger of one of the red parts spinning in front of the core, STOP LASERING and wait for an opening to show up. Don't get greedy and blow yourself up now -- it'd be a pain to do this all over again. Congratulations, you dismantled the bomb! -------------------------------------------------------------------------------- Episode 3-8: Caduceus on a Plane [3.08] Overview: Edema of the lungs has worsened, causing respiratory failure. Fluid must be drained from the lungs to secure the respiratory tract. Objectives: * Drain pleural fluid from inside the patient's lungs. GUILT Faced: (none) -------------------------------------------------------------------------------- First off, kudos to Atlus's translation team for the Snakes On A Plane reference. Anyhow, this mission is easy with one exception -- periodically, the plane will encounter turbulence and you'll have to stop whatever you're doing. I'm serious, too -- using anything, even using the ultrasound, during turbulence will cause lacerations and mess up your patient's vitals. So don't do it! When turbulence comes and the screen starts shaking, just take your fingers off of the A & B buttons. It's safer that way. Between rounds of turbulence, all you have to do is ping around with the ultrasound and find the pockets of fluid. Once you find one (it will show up as a black splotch), slice it open with the scalpel and drain the fluid, then gel the cut. Repeat about a dozen times and then you're done. Just be sure to watch out for the turbulence! Not even the ultrasound is safe during those times, so just be patient. -------------------------------------------------------------------------------- Episode 3-10: Pandora's Box [3.10] Overview: Chiral reaction positive -- unknown infection detected. Extreme care is necessary during treatment. Objectives: * Remove the GUILT. GUILT Faced: Triti -------------------------------------------------------------------------------- Oh boy. Triti is the most pain-in-the-ass GUILT in the game in my opinion, and for all that everyone says that it's easy, I still have problems. Since I still have issues with this type of GUILT, I'll just give you a few key pointers: * Triti will spread in places where there are multiple thorns adjacent to each other, so, try to pull out thorns so that there are gaps between all of them. * If any triangle or segment becomes isolated (separated) from the main "body" of Triti, that segment will grow rapidly, so try to keep everything connected. * The darker-colored triangles cause extra damage to the patient's vitals, so try to excise them quickly if possible. * Back the Triti into a corner so that it can't regenerate as easily. That is, if you're working on its lower-right corner, make sure that it's pushed all the way up into the upper-left corner (so that it can't keep growing in that direction). Other than that, cross your fingers. Every guide out there seems to have some magic winning formula for Triti, but none of them seem to ever work perfectly for me. Good luck, and remember that your Healing Touch is there if you need it, though I would save it for the very end when you're just about done. ----------------------------------------------------- Ryn writes: "A lot of people seem to have trouble with Triti because they don't understand the regeneration pattern. It is basically this: IF THERE ARE TWO THORNS NEXT TO EACH OTHER AND THERE IS FREE SPACE FOR GROWTH IT WILL REGENERATE. This being said, there are two fairly quick and simple ways to dispose of it. 1) You can use your HT and extract every thorn and every membrane all at once (yes is possible I have done it myself), but it requires fast movement and precision. Only for use by very experienced players that somehow still have a hell of a lot of trouble with Triti (like me :D). 2) Like every other strategy in the world, back it into a corner. Don't treat the thorns and membranes like a whole bunch of different things that need to be taken out at random, but rather treat them as diagonal rows of each, with the membrane rows being between the thorn rows, sorta like reading between the lines. This being said, extract thorn rows 1 and 2, extract membrane row 1, rinse and repeat. In the beginning the membranes will almost always regen, making it SEEM like you are getting nowhere, but just stick with the 2 rows - 1 row and eventually the membranes will be so far into the corner that you can extract al the thorns and membranes left without the need of a HT throughout the whole mission. Oh yeah. If a thorn vaporizes it WILL slow you down a bit but just keep your concentration, drain the fumes, and continue extracting." ----------------------------------------------------- -------------------------------------------------------------------------------- Episode Z-3: Pursuit [Z.03] Overview: External trauma and lacerations have occurred. May be an abnormality in patient's abdomen. Visibility is poor; resources are far from ideal. Objectives: * Extract any foreign objects. * Suture any lacerations. GUILT Faced: (none) -------------------------------------------------------------------------------- This one is fun. You'll be operating on a car crash victim in the dark. Well, relative dark. You'll have a penlight that you'll need to position (using the pointer and locking it in place with the A button) while you work. Other than the issues with light, this goes exactly like one of the very first missions in the game, so just extract the glass shards and suture the wounds. After a short while, the penlight batteries will die, so you'll use a camera flash instead. Just click the camera flash button, and the screen will light up briefly, then begin to fade. Work as fast as you can, and re-flash the camera whenever you need it. Congratulations, you just totally MacGyvered that operation. -------------------------------------------------------------------------------- Episode 4-2: Race For The Cure [4.02] Overview: Chiral reaction positive -- Tetarti bodies detected. Extract GUILT to procure antibody samples for analysis. Objectives: * Obtain three different samples to develop a cure. GUILT Faced: Tetarti (immature) -------------------------------------------------------------------------------- In this mission, you'll get to operate on several patients, and you can choose where you get to go. Not that it really matters, but the game gives you the choice anyway. The objective is to find three different specimens of Tetarti, a new strain of GUILT. To do so, you'll have to: * Inject the serum into the GUILT to kill it. * Ultrasound it to find it again, then cut it out and inject some more serum. * Repeat until it dies. * Once it's dead, place it on the tray, cut it open, and then suck out its insides with the drain. Repeat this with as many patients as necessary until Angie tells you that you have all of the samples that you need. -------------------------------------------------------------------------------- Episode 4-4: Stepping Up [4.04] Overview: Tetarti bodies confirmed in the patient's liver. Inject the newly designed serum to eliminate the GUILT. Objectives: * Kill the GUILT cells in his liver by injecting the correct serums. GUILT Faced: Tetarti (mature) -------------------------------------------------------------------------------- These Tetarti require a different approach than the ones you faced before, but they're not really any harder. In this operation (and all subsequent ones), the Tetarti come in three colors -- green, yellow, and purple. Notice that you have three colors of serum -- green, yellow, and purple. Figured it out yet? First off, there are three diverticula (little tumors, basically) that come in those three colors as well. Inject the serums into the diverticula to take care of them, and then the GUILT comes along. Basically, you need to inject each serum into the matching-color Tetarti. The trick comes in that after the Tetarti appear, they only show their colors for a second before they all turn colorless, so you'll have to memorize which one is which, then inject them all with the correct serum. Repeat this a few times (it shouldn't be too hard), and they'll die. If you inject the wrong one, raise his vitals a bit and take care of any diverticula that may appear. If you miss the GUILT and just jab the needle into the patient's liver, don't worry about it and just raise his vitals if you do too much damage. That's all there is to it! Really, just memorize which one is which color and you've got it in the bag. It's even easier if you have a friend watching so you can both remember the colors. -------------------------------------------------------------------------------- Episode 4-6: The First Step [4.06] Overview: Chiral reaction positive -- Pempti bodies detected. Perform a lobectomy and examine the strain for further study. Objectives: * Do everything I tell you to do. GUILT Faced: Pempti -------------------------------------------------------------------------------- There's not much to say other than what the objective says -- do whatever Victor says. He'll have you try various things on the Pempti, none of which seem to really work. First you'll try various tools, and then he'll ask you to inject various combinations of serums. Once you've done everything he asks, you can cut out a little piece of the Pempti for Victor to examine. After that's done, close up the patient and let Victor do his research. -------------------------------------------------------------------------------- Episode 4-7: Medical Research [4.07] Overview: Help create a new nanomachine by figuring out a simple puzzle. How hard could it be? Objectives: * Solve the puzzle. GUILT Faced: (none) -------------------------------------------------------------------------------- Not much to say here. If you take a long time, you'll get a bunch of amusing quips from all of the other doctors about your mental abilities. It's pretty funny, actually. Here's the solution: * * R R O R O G W O R W G * W G W -------------------------------------------------------------------------------- Episode 4-8: The Next Step [4.08] Overview: Chiral reaction positive -- Pempti bodies found. Lung functions have decreased due to GUILT invasion. New treatment is scheduled for trial. Objectives: * Perform a lobectomy and inject the nanomachine directly. * Then, excise the GUILT and any surrounding tissue. GUILT Faced: Pempti -------------------------------------------------------------------------------- Have you got what you need? Will you be able to kill the Pempti this time? Let's find out. Inject the nanomachine (the orange serum) into the core of the Pempti a few times. The Pempti will shrink each time you do it. Once the core becomes exposed, pull out your laser and start burning it. It looks dead, but...no! It comes back! Damn. Victor will tell you to try again, so repeat the procedure. This time, you can excise the core after you've lasered it. Still no good! The core replicates itself whenever you damage or remove it. Victor tells you to do it again, but Sidney orders you to stop. Close up the patient and it's time for more puzzles! Throughout this mission, you may see small polyps/tumors formed on the patient's lungs. Laser them off and gel the burn marks if necessary, and keep an eye on his vitals. This should go without saying, though -- but it's important nonetheless. -------------------------------------------------------------------------------- Episode 4-9: Progress [4.09] Overview: Help create a new device by figuring out another simple puzzle. No sweat, right? Objectives: * Solve the puzzles. GUILT Faced: (none) -------------------------------------------------------------------------------- Two puzzles this time. Nothing to say, so let's jump to the solutions for you lazy folks who don't want to figure it out for yourselves: R R R W R P B W R * W R P B * P P W G O O G G O And the second one: Y Y B G Y B O G Y B G Y R O P * O P P R O P R R -------------------------------------------------------------------------------- Episode 4-10: Prolonged Struggle [4.10] Overview: Chiral reaction positive -- Pempti bodies found. Lung condition has dropped to critical. Prototype laser treatment is the only option. Objectives: * Use the nanomachine to lure out the core, just like last time. * Use our new laser to destroy the core as it tries to regenerate tissue. GUILT Faced: Pempti -------------------------------------------------------------------------------- Finally we'll be able to kill this thing, once and for all. Begin as usual -- inject the nanomachine to shrink it, then the core will become exposed. Once the core appears, it will begin attacking by creating mini-cores. The mini-cores come in two varieties: pink and blue. The pink ones, if not killed immediately, will fly to the top of the screen and leave really big lacerations in their wake. These can add up quickly if there are five pink guys flying around, so do whatever you can to make sure that you kill all of the pink ones as soon as they're created! If one or two slip through, it's okay, but all five creating lacerations repeatedly will kill your patient in a heartbeat. On a regular basis, the Pempti will "wash" over the screen and all blue mini- cores that are present at that time will create a bunch of polyps. Burn them away and gel them ASAP, or else the next time that the Pempti "washes" up the screen, all of the polyps will burst and deal damage. Try to at least remove most of them, though leaving a few behind in the interest of saving time probably won't spell the end of the world for you. Between attacks (if your vitals are looking okay), laser the core as much as possible. The mini-cores should always be your top priority (as well as cleaning up any lacerations/polyps that they may leave behind), but whenever you have a spare moment, try to deal some damage to the core. The only way that you'll win this mission is to laser the core a whole lot, so keep at it! Once the core dies, you can close up the patient because that's all there is to it. Congratulations! You've beaten one of the most dangerous GUILT there is. -------------------------------------------------------------------------------- Episode Z-4: Transplant [Z.04] Overview: Kidney transplant. Perform anastomosis to slow blood flow, then proceed quickly. Tumors have been confirmed and must be extracted first. Objectives: * Tumor excision. * Transplanting the new kidney. GUILT Faced: (none) -------------------------------------------------------------------------------- This mission can get out of hand quickly if you're not quick about it. Basically, you need to remove the tumors as you've done before, which shouldn't really be a problem. Once those are taken care of, you need to inject the serum to constrict the patient's veins and then connect the kidney's veins to the patient's. First, constrict the vein (the blue one), cut it open, and then connect the kidney to it, finishing up with a suture. Move quickly, and inject some more serum if the vein gets too large and begins bleeding heavily. Repeat the process with the artery (the red one). Finally, do the same with the green part, though you don't need to inject any serum into this one as it's not a blood vessel. If you have problems with vitals in this mission (which is entirely possible), don't be afraid to use the Healing Touch (that's right, Dr. Weaver has it too), especially on the higher difficulties. -------------------------------------------------------------------------------- Episode 5-2: Under the Knife [5.02] Overview: Chiral reaction positive -- Kyriaki bodies detected. Multiple patients are in need of immediate attention. Objectives: * Remove the Kyriaki from as many patients as possible. GUILT Faced: Kyriaki -------------------------------------------------------------------------------- This is fun, but depends entirely on your ability to act fast and your familiarity with Kyriaki. You have five patients that are all infected with Kyriaki, and it's up to you to save as many of them as possible. In the DS version, as long as you were on the third patient when time expired, you passed the mission, but I don't know if that's still true in this version. In any case, work as fast as you can and try to get through all five patients if possible. Nothing really new to say here -- kill all of the Kyriaki just like you've done multiple times before, and keep an eye on those vitals. Save the lacerations for the end after all of the Kyriaki are dead if you can manage to keep the patient's vitals high enough. Good luck. -------------------------------------------------------------------------------- Episode 5-3: Shifting GUILT [5.03] Overview: Chiral reaction positive -- Triti bodies detected. Airborne properties create a high risk of infection. Quick work is advised. Objectives: * Remove the Triti and prevent it from infecting others. GUILT Faced: Triti -------------------------------------------------------------------------------- More Triti. Ugh. This mission is largely the same as 3-10: "Pandora's Box," so just follow the pointers that I outlined in that mission (or in the GUILT Strategies section). Good luck -- you may very well need it. -------------------------------------------------------------------------------- Episode 5-4: GUILT Evolves [5.04] Overview: Chiral reaction positive -- Tetarti bodies detected. This mutation is resistant to serum and much stronger than before. Objectives: * Remove the Tetarti. GUILT Faced: Tetarti -------------------------------------------------------------------------------- Once again, this is another mission that you've basically done before. This one is a little harder, though -- the Tetarti will take longer to kill and will not show their colors as much. If you have trouble identifying which is which, you can look at the color of the poison clouds that they each emit -- those match up with their serum colors as well. After injecting each of the little buggers several times, they'll give up the ghost. Moving on. -------------------------------------------------------------------------------- Episode 5-6: Infection [5.06] Overview: Chiral reaction positive -- Paraskevi bodies detected. Immediate removal is necessary before they can reach the patient's heart. Objectives: * Remove the GUILT. GUILT Faced: Paraskevi -------------------------------------------------------------------------------- Ah, a new one! This is one to be careful of. Here's the basic facts on our new friend Paraskevi: * There are four "zones" in this operation, the Paraskevi starts out in the intestines and works its way up to the heart. * If the Paraskevi reaches the heart, the patient instantly dies and it's game over, so don't let that happen, okay? * Paraskevi is too big to extract -- you will have to cut it down into many smaller pieces and extract them one by one. Start by cutting it in half, then cutting each of those pieces in half, then those in half, etc. Eventually you will be able to extract the smallest pieces. * You can stun Paraskevi by lasering its tail. This also holds true for individual Paraskevi segments. As far as I know you *must* stun the Paraskevi before you can extract them, but mainly it's important to keep them stunned at all times so that they don't move on to the next zone. That's about it. Stun it, scalpel it, stun both halves, scalpel one of them, stun those pieces, scalpel them, etc. Try to keep as many pieces stunned as possible at all times. If a few pieces escape to the next area, don't sweat it too much, but try not to let anything leave the area. Keeping all of the pieces stunned is key. If you continue to have trouble or just want another persons' viewpoint, there's a reader-submitted strategy in the GUILT strategies section, do a Find for [G.06] to jump straight there. Once you extract all of the pieces, Cybil is saved. Congratulations. I guess this is payback for her helping you dismantle that bomb earlier. -------------------------------------------------------------------------------- Episode 5-8: A Devil [5.08] Overview: Chiral reaction positive -- unknown infection detected. Extreme care is required during the treatment procedure. Objectives: * Remove the GUILT. GUILT Faced: Savato (immature) -------------------------------------------------------------------------------- Don't let this mission fool you -- this may be Savato, but these are just the babies. You'll fight the real one next time. There's not a whole lot going on in this mission -- just laser all of the babies that you see. Occasionally, five babies will join together to create a bigger blue bug -- kill these ones ASAP, as they lower your maximum vitals level by quite a bit. Having multiple ones on the screen at once will lower your maximum vitals to 35 or even lower. Eek! Towards the end, tons and tons of little babies will pop out -- do your best to laser them all, and I suppose you could use your Healing Touch if you really wanted to. Make sure that you kill all of the big blue ones as soon as they appear, and raise his vitals if you need to. This is just a warm-up for next time, so don't get too cocky. -------------------------------------------------------------------------------- Episode 5-9: Death Awaits All [5.09] Overview: Chiral reaction positive -- unknown infection detected. Pulse has dropped, so cardiac complications are extremely likely. Objectives: * Defeat the GUILT and save Dr. Blackwell. GUILT Faced: Savato (mature) ------------------------------------------------------------------------
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